Global improvement in right ventricular function after Stage II Norwood operation in children with hypoplastic left heart assessed by serial MRI
2011

Improvement in Heart Function After Surgery in Children

Sample size: 51 publication Evidence: moderate

Author Information

Author(s): Hannah R Bellsham-Revell, Reza Razavi, Philipp Beerbaum, Gerald Greil, Aaron Bell

Primary Institution: King's College London

Hypothesis

Can right ventricular function improve in children with hypoplastic left heart syndrome after Stage II Norwood operation?

Conclusion

Children with hypoplastic left heart syndrome showed improved right ventricular function after Stage II surgery.

Supporting Evidence

  • 51 patients had an analysable MRI scan before Stage II and before Stage III.
  • 21 patients had an RV EF >50% on the pre-Stage II MRI.
  • The RV indexed end diastolic volume fell in both groups from the first to the second MRI.
  • RV EF increased by 22.8% in the RV EF >50% group.
  • The greatest increase in RV EF was seen in the group with an RV EF <50% who had Stage II at less than 6 months of age.

Takeaway

Doctors looked at kids' hearts before and after a surgery to see if their heart function got better, and it did!

Methodology

MRI scans were analyzed to assess right ventricular volumes and function before Stage II and Stage III surgeries.

Participant Demographics

Children with hypoplastic left heart syndrome, median age 0.343 years for those with EF <50% and 0.465 years for those with EF >50%.

Digital Object Identifier (DOI)

10.1186/1532-429X-13-S1-P186

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