ESBL Carriage in the Malagasy Community
Author Information
Author(s): Herindrainy Perlinot, Randrianirina Frédérique, Ratovoson Rila, Ratsima Hariniana Elisoa, Buisson Yves, Genel Nathalie, Decré Dominique, Arlet Guillaume, Talarmin Antoine, Richard Vincent
Primary Institution: Institut Pasteur de Madagascar
Hypothesis
What is the prevalence and risk factors of intestinal carriage of ESBL-producing bacteria in the community of Antananarivo?
Conclusion
The prevalence of ESBL carriage in the community of Antananarivo is alarmingly high at 10.1%, primarily associated with poverty.
Supporting Evidence
- The study found a carrier rate of 10.1% for ESBL-producing bacteria.
- Poverty was identified as the predominant risk factor for ESBL carriage.
- The study included 484 patients from various socioeconomic backgrounds.
Takeaway
This study found that many people in Antananarivo carry bacteria that are resistant to common antibiotics, mostly because they are poor and have less access to good hygiene.
Methodology
Non-hospitalized patients were recruited from three health centers, and stool samples were tested for ESBL-producing bacteria using specific culture and molecular methods.
Potential Biases
Potential bias due to self-reported socioeconomic status and exclusion of patients with recent antibiotic use.
Limitations
The study only included non-hospitalized patients and may not represent the entire population.
Participant Demographics
Median age of participants was 28 years, with a sex ratio of 1.03 (male to female).
Statistical Information
P-Value
0.02
Confidence Interval
[1.6-53.9]
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website