A randomized controlled trial of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin-resistant Staphylococcus aureus (MRSA) in critically ill adults: research protocol
2008

Using Tea Tree Oil to Prevent MRSA in ICU Patients

Sample size: 1080 publication Evidence: moderate

Author Information

Author(s): Gillian Thompson, Bronagh Blackwood, Ronan McMullan, Fiona A Alderdice, T John Trinder, Gavin G Lavery, Danny F McAuley

Primary Institution: Belfast Health & Social Care Trust

Hypothesis

MRSA colonization among critically ill patients will be reduced by daily washing with 5% TTO body wash in comparison with a standard body wash.

Conclusion

If effective, TTO body wash could significantly improve patient outcomes and reduce healthcare costs associated with MRSA infections.

Supporting Evidence

  • MRSA is a major concern in ICUs due to its high incidence and associated healthcare costs.
  • Tea tree oil has shown effectiveness in eradicating MRSA skin colonization in previous studies.
  • The study aims to provide a faster method for MRSA detection using a PCR assay.

Takeaway

This study is testing if washing patients with tea tree oil can help stop them from getting a skin germ called MRSA, which can make them very sick.

Methodology

A multicentre, phase II/III prospective open-label randomized controlled trial comparing 5% TTO body wash with standard body wash in ICU patients.

Potential Biases

Potential bias in randomization and patient selection due to the critical condition of participants.

Limitations

The study may not account for all variables affecting MRSA colonization and relies on patient compliance.

Participant Demographics

Critically ill adults in two ICUs in Northern Ireland.

Statistical Information

P-Value

0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2334-8-161

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