Autoimmune liver disease - are there spectra that we do not know?
2011

Unusual Forms of Autoimmune Liver Disease

Sample size: 3 publication Evidence: low

Author Information

Author(s): Hind I Fallatah, Akbar Hisham O

Primary Institution: King Abdul Aziz University Hospital, Jeddah, Saudi Arabia

Hypothesis

Are there unknown spectra of autoimmune liver diseases?

Conclusion

The study presents three case reports of atypical autoimmune liver diseases that progressed to advanced cirrhosis despite treatment.

Supporting Evidence

  • Autoimmune liver diseases are common causes of liver cirrhosis.
  • Patients with autoimmune hepatitis often respond to treatment with prednisolone and azathioprine.
  • Primary biliary cirrhosis has a good long-term outcome with ursodeoxycholic acid treatment.

Takeaway

This study talks about three patients with rare types of liver disease that didn't get better with usual treatments and got worse over time.

Methodology

Case reports of three patients with unusual presentations of autoimmune liver diseases were analyzed.

Limitations

The study is based on only three case reports, limiting the generalizability of the findings.

Participant Demographics

Three patients: one female from Chad, one male from Saudi Arabia, and one male from India, aged 27, 30, and 36 respectively.

Digital Object Identifier (DOI)

10.1186/1476-5926-10-9

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