Two Immigrants with Tuberculosis of the Ear, Nose, and Throat Region with Skull Base and Cranial Nerve Involvement
2011
Two Immigrants with Tuberculosis of the Ear, Nose, and Throat Region
Sample size: 2
publication
Evidence: low
Author Information
Author(s): Richardus Renate A., Jansen Jeroen C., Steens Stefan C. A., Arend Sandra M.
Primary Institution: Leiden University Medical Center
Conclusion
The cases illustrate the importance of considering tuberculosis in the differential diagnosis of unexplained ENT problems.
Supporting Evidence
- Both patients had positive Quantiferon TB Gold results.
- Imaging showed significant involvement of the skull base and cranial nerves.
- Histology confirmed necrotizing granulomatous inflammation.
Takeaway
This study talks about two people who had a rare type of tuberculosis that affected their ears, nose, and throat, showing how tricky it can be to diagnose.
Methodology
The study involved case reports of two patients with tuberculosis affecting the ENT region, including imaging and laboratory tests.
Limitations
The study is based on only two case reports, limiting generalizability.
Participant Demographics
Two male immigrants, one from Somalia and one from Sudan.
Digital Object Identifier (DOI)
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