Trends in total cholesterol screening and in prescribing lipid-lowering drugs in general practice in the period 1994–2003
2008

Trends in Cholesterol Screening and Lipid-Lowering Drug Prescribing

Sample size: 139148 publication Evidence: moderate

Author Information

Author(s): Bartholomeeusen Stefaan, Vandenbroucke Jan P, Truyers Carla, Buntinx Frank

Primary Institution: Katholieke Universiteit Leuven

Hypothesis

How have cholesterol screening and the prescription of lipid-lowering drugs changed in general practice from 1994 to 2003?

Conclusion

Cholesterol testing and treatment practices have broadened significantly, with more patients being tested and treated at lower cholesterol levels than in previous years.

Supporting Evidence

  • Cholesterol testing increased in all age groups, especially for those over 65.
  • 12% of patients tested were on lipid-lowering medication.
  • The mean cholesterol level decreased in both treated and untreated groups.

Takeaway

Doctors are checking cholesterol levels more often and starting patients on cholesterol-lowering medications sooner than before.

Methodology

Data from the Intego database, including electronic medical records from 47 general practices, were analyzed using mixed model linear regression.

Potential Biases

The study may not fully represent all Flemish GPs due to selection based on registration quality.

Limitations

The GPs in the study were not a random sample, and there may have been unrecorded tests performed by hospital consultants.

Participant Demographics

54.56% women and 45.44% men, with a focus on patients over the age of 25.

Statistical Information

P-Value

<0.0001

Confidence Interval

95% CI for differences in cholesterol levels reported in the results.

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1471-2296-9-39

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