GENDER DIFFERENCES IN DEPRESSIVE SYMPTOMS’ IMPACT ON CHRONIC DISEASES, FUNCTIONAL LIMITATIONS, AND MORTALITY
2024

Gender Differences in Depression's Impact on Health in Older Adults

Sample size: 857 publication Evidence: moderate

Author Information

Author(s): Ahn Seoyeon, Visaria Abhijit, Malhotra Rahul, Chan Angelique

Primary Institution: Duke-NUS Medical School

Hypothesis

How do depressive symptoms influence chronic diseases, functional limitations, and mortality in older adults?

Conclusion

Men and women experience different health trajectories, with depressive symptoms accelerating health decline in both genders.

Supporting Evidence

  • Men had higher mortality rates but slower progression in chronic pain and physical decline.
  • Women lived longer but had earlier onset and faster progression of chronic pain and functional decline.
  • Depressive symptoms were linked with faster onset of chronic diseases and functional limitations in both genders.

Takeaway

This study shows that men and women age differently when it comes to health problems, and feeling sad can make these problems worse.

Methodology

The study used multichannel sequence analysis and random-effects logistic regression on data from three waves of the Panel on Health and Aging of Singaporean Elderly.

Potential Biases

Selection bias due to loss to follow-up was addressed using inverse probability of attrition weights.

Limitations

The study may be limited by the specific demographic of Singaporean elderly and potential biases in self-reported data.

Participant Demographics

Participants were aged 60-69 years, with 386 men and 471 women.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.3988

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