Kidney Injury After Heart Procedures
Author Information
Author(s): Hamzaraj Kevin, Demirel Caglayan, Gyöngyösi Mariann, Bartko Philipp E., Hengstenberg Christian, Frey Bernhard, Hemetsberger Rayyan, Martínez-Sellés Manuel, Giallauria Francesco
Primary Institution: Medical University of Vienna
Hypothesis
Is contrast-associated acute kidney injury related to worse short- and long-term mortality after chronic total occlusion percutaneous coronary intervention?
Conclusion
Contrast-associated acute kidney injury was found to be an independent predictor of all-cause mortality at one year but not at three years.
Supporting Evidence
- Patients with contrast-associated acute kidney injury had a higher one-year mortality rate of 16.7% compared to 5.5% in those without.
- CA-AKI was an independent predictor of one-year mortality with an adjusted hazard ratio of 5.3.
- Longer procedures and higher radiation doses were associated with an increased risk of developing CA-AKI.
Takeaway
This study looked at patients who had heart procedures and found that those who had kidney injury from the contrast used during the procedure were more likely to die within a year.
Methodology
This was a single-center retrospective analysis of patients undergoing chronic total occlusion percutaneous coronary intervention, comparing those who developed contrast-associated acute kidney injury with those who did not.
Potential Biases
Selection bias may have occurred as patients without available postprocedural creatinine levels were excluded.
Limitations
The study is retrospective and may have selection bias due to missing follow-up creatinine levels.
Participant Demographics
Mean age of 67 years, 75% male, with 33.1% having diabetes and 76.6% having hypertension.
Statistical Information
P-Value
0.009
Confidence Interval
[1.52–18.51]
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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