Precursor B-cell acute lymphoblastic leukemia presenting as obstructive jaundice: a case report
2011
Case of Leukemia Presenting as Jaundice
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Siddique Muhammad N, Popalzai Muhammad, Aoun Nelly, Maroun Rabih, Awasum Michael, Dai Qun
Primary Institution: Staten Island University Hospital
Hypothesis
Can precursor B-cell acute lymphoblastic leukemia present with jaundice in adults?
Conclusion
Acute lymphoblastic leukemia can present with jaundice, which may complicate diagnosis and treatment.
Supporting Evidence
- The patient presented with jaundice and abdominal pain.
- Initial tests showed pancytopenia and hyperbilirubinemia.
- Liver biopsy revealed lymphocytic infiltration consistent with leukemia.
- Bone marrow biopsy confirmed the diagnosis of precursor B-cell acute lymphoblastic leukemia.
Takeaway
A man got very sick with jaundice because of a type of blood cancer called leukemia, which is usually not seen with jaundice.
Methodology
The patient underwent blood tests, imaging studies, a liver biopsy, and a bone marrow biopsy to confirm the diagnosis.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
44-year-old Hispanic male.
Digital Object Identifier (DOI)
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