Cognition, Anxiety, and Treatment Adherence in Hypertensive Patients
Author Information
Author(s): Jacobs Úrsula, De Castro Mauro S., Fuchs Flávio D., Ferreira Maria Beatriz C.
Primary Institution: Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil
Hypothesis
Does cognition affect drug adherence?
Conclusion
Cognitive deficit impairs adherence to drug therapy and should be screened as part of a program of pharmaceutical care to improve adherence to treatment.
Supporting Evidence
- Participants with an unsatisfactory score in the Mini-mental had six-fold higher risk of non-adherence to treatment.
- All non-adherent patients showed at least one altered test for immediate memory.
- The proportion of patients with normal score in the Mini-mental was greater in the adherence group.
Takeaway
If someone has trouble thinking clearly, they might forget to take their medicine, which can make them sick.
Methodology
This is a cohort study with 56 adult patients with uncontrolled hypertension who participated in a randomized clinical trial of pharmaceutical care.
Potential Biases
Potential beta error due to small sample size.
Limitations
The small sample size and the selection criteria may have excluded participants with significant psychiatric disorders or high anxiety.
Participant Demographics
Adult patients over 18 years of age with uncontrolled hypertension.
Statistical Information
P-Value
0.007
Confidence Interval
1.6–20.8
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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