Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial

2011

Effect of Tylosin on Dogs with Diarrhea

Sample size: 61 publication Evidence: moderate

Author Information

Author(s): Kilpinen Susanne, Spillmann Thomas, Syrjä Pernilla, Skrzypczak Teresa, Louhelainen Maria, Westermarck Elias

Primary Institution: University of Helsinki

Is tylosin effective in treating dogs with suspected tylosin-responsive diarrhea compared to a placebo?

Tylosin is effective in treating recurrent diarrhea in dogs, with 85% of treated dogs showing normal fecal consistency.

85% of dogs treated with tylosin had normal fecal consistency compared to 29% in the placebo group.
Diarrhea recurred in 43.3% of dogs during the follow-up period.
Fecal consistency was evaluated using a nine-point scale.

Tylosin helps dogs with diarrhea feel better, and most dogs treated with it stop having diarrhea.

71 client-owned dogs were randomly assigned to receive either tylosin or placebo, and fecal consistency was evaluated over a two-month follow-up.

Potential bias due to owner-reported outcomes and the subjective nature of fecal consistency evaluation.

The study had a small sample size and the etiology of diarrhea in dogs remains unclear.

Dogs aged 6 months to 13 years, with a median age of 3 years and 4 months, consisting of 33 different breeds.

0.0049

p<0.05

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