The human solute carrier family 11 member 1 protein (SLC11A1): linking infections, autoimmunity and cancer?
2007
The Role of SLC11A1 in Infections, Autoimmunity, and Cancer
publication
Evidence: moderate
Author Information
Author(s): Awomoyi Agnes A
Primary Institution: University of Maryland School of Medicine
Hypothesis
How does the SLC11A1 protein link infections, autoimmunity, and cancer?
Conclusion
SLC11A1 plays a significant role in linking chronic inflammation to infections, autoimmunity, and cancer.
Supporting Evidence
- SLC11A1 is associated with chronic inflammation, which can lead to cancer and autoimmune diseases.
- Different alleles of SLC11A1 influence susceptibility to infections and autoimmune diseases.
- Chronic inflammation can result from various infections, which are linked to SLC11A1 function.
Takeaway
SLC11A1 is a protein that helps our body fight infections, but if it works too much, it can also lead to diseases like cancer and autoimmune disorders.
Methodology
This is a review discussing the mechanisms of SLC11A1 in relation to infections, autoimmunity, and cancer.
Digital Object Identifier (DOI)
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