Peripartum cardiomyopathy: a KKH case series
2011

Peripartum Cardiomyopathy Case Series

Sample size: 7 publication Evidence: low

Author Information

Author(s): Shah MK, Leo S, Ocampo CE, Yim CF, Tagore S

Primary Institution: Kandang Kerbau Women's and Children's Hospital, Singapore

Hypothesis

What are the incidence, presentation, and risk factors of peripartum cardiomyopathy in Singapore?

Conclusion

The study found that possible risk factors for peripartum cardiomyopathy include multiparity, preterm labor requiring tocolysis, prostin induction of labor, and postpartum hemorrhage.

Supporting Evidence

  • Incidence of peripartum cardiomyopathy was found to be 1:2,285 deliveries.
  • Symptoms appeared from 1 hour post-delivery to postpartum day 5.
  • All patients experienced dyspnoea and evidence of pulmonary congestion.
  • Troponin I and CKMB levels were raised in most cases.
  • Median follow-up showed 4 out of 7 patients made a full recovery.

Takeaway

This study looked at seven women who had heart problems after giving birth and found some reasons why this might happen.

Methodology

Case notes of seven patients were reviewed following IRB approval.

Limitations

The study is limited by its small sample size and retrospective design.

Participant Demographics

All participants were Asian except for one German, with a mean age of 29.7 years.

Statistical Information

Confidence Interval

25% (19 to 35)% for worst LVEF at diagnosis; 55% (35 to 65)% for last LVEF.

Digital Object Identifier (DOI)

10.1186/cc9433

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