GLYNAC SUPPLEMENTATION LOWERS POSTPRANDIAL INFLAMMATION AND OXIDATIVE STRESS TO PROMOTE HEALTH IN OLDER HUMANS
2024

GlyNAC Supplementation Reduces Inflammation and Oxidative Stress in Older Adults

Sample size: 30 publication Evidence: high

Author Information

Author(s): Sekhar Rajagopal, Kumar Premranjan, Taffet George, Minard Charles

Primary Institution: Baylor College of Medicine

Hypothesis

Does GlyNAC supplementation lower postprandial inflammation and oxidative stress in older adults compared to a placebo?

Conclusion

GlyNAC supplementation protects older adults from increases in oxidative stress and inflammation after consuming a carbohydrate meal.

Supporting Evidence

  • Older adults had significantly higher postprandial increases in oxidative stress and inflammation compared to young adults before supplementation.
  • GlyNAC supplementation significantly reduced postprandial oxidative stress and inflammation in older adults.

Takeaway

Older people can feel better after eating if they take a special supplement called GlyNAC, which helps reduce bad reactions in their bodies.

Methodology

A randomized clinical trial comparing the effects of GlyNAC supplementation versus placebo on postprandial oxidative stress and inflammation in older and young adults.

Participant Demographics

20 older adults and 10 young adults participated in the study.

Statistical Information

P-Value

p=0.03

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0415

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