Study on Occupational Allergy Risks (SOLAR II) in Germany: Design and methods
2011

Study on Occupational Allergy Risks in Germany

Sample size: 2904 publication Evidence: moderate

Author Information

Author(s): Heinrich Sabine, Peters Astrid, Kellberger Jessica, Ellenberg Diana, Genuneit Jon, Nowak Dennis, Vogelberg Christian, Mutius Erika, Weinmayr Gudrun, Radon Katja

Primary Institution: University Hospital of Munich (LMU), Munich, Germany

Hypothesis

What are the environmental and occupational risk factors affecting the course of atopic diseases from childhood to young adulthood?

Conclusion

A 12-year follow-up from childhood to adulthood is feasible, resulting in a response of 32% of the baseline population.

Supporting Evidence

  • 2904 participants were contacted on average five years after the first follow-up.
  • 71% of those contacted completed the questionnaire.
  • 57% of questionnaire respondents participated in clinical examinations.
  • Selection bias was noted as responders had higher parental education levels.

Takeaway

This study followed young adults to see how their allergies and asthma changed as they grew up and started working.

Methodology

Participants completed questionnaires and underwent clinical examinations including skin prick tests and spirometry.

Potential Biases

Participants with higher parental education and atopy were more likely to respond, indicating potential selection bias.

Limitations

High mobility of participants and limited interest in the study affected response rates.

Participant Demographics

Young adults aged 19 to 24, with a focus on those who had participated in earlier studies.

Digital Object Identifier (DOI)

10.1186/1471-2458-11-298

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