Bullous Pemphigoid Onset Following Vaccination in Infancy: A Case Report
2024

Bullous Pemphigoid After Vaccination in Infancy: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Hassanin Sondos, Katira Arnav, Hardcastle Nicola

Primary Institution: Sheffield Children's Hospital

Hypothesis

Is there a potential link between bullous pemphigoid and vaccination in infants?

Conclusion

The case highlights the need for further investigation into the potential association between bullous pemphigoid and vaccination.

Supporting Evidence

  • The infant developed bullous pemphigoid four days after routine vaccinations.
  • Immunological analysis showed weak positivity for anti-BP180 antibodies.
  • The patient responded well to systemic therapy including corticosteroids and IVIG.

Takeaway

This study talks about a baby who got a skin disease after getting vaccinated, and it shows that we need to look more into how vaccines might affect some kids.

Methodology

Case report detailing the clinical presentation, treatment, and outcomes of a four-month-old infant with bullous pemphigoid following vaccination.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

Four-month-old male infant, exclusively breastfed, with no relevant family history.

Digital Object Identifier (DOI)

10.7759/cureus.76017

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