Inflammatory Myofibroblastic Tumor of the Trachea with Granulomatous Lymph Node Lesions
Author Information
Author(s): Julia Anne Koch, Patrick Dorn, Thierry Rausch, Hans-Beat Ris, Hans-Anton Lehr, Stephan C. Schäfer
Primary Institution: CHUV, Lausanne, Switzerland
Hypothesis
What is the pathophysiological link between the inflammatory myofibroblastic tumor in the trachea and the granulomatous lesions in the lymph nodes?
Conclusion
The authors suggest that the granulomatous reaction in the lymph nodes may be a response to the inflammatory myofibroblastic tumor in the trachea.
Supporting Evidence
- The tracheal tumor was diagnosed as an inflammatory myofibroblastic tumor confirmed by ALK-1 positivity.
- The granulomatous lesions in the lymph nodes were diagnosed as sarcoid-like lesions.
- The patient showed no evidence of tumor recurrence or systemic dissemination 24 months after surgery.
Takeaway
A 57-year-old woman had a tumor in her trachea and swollen lymph nodes, and doctors think the two might be connected.
Methodology
The case involved histological examination, immunohistochemistry, and surgical resection of the lesions.
Limitations
The interpretation of the relationship between the two lesions remains speculative and lacks conclusive evidence.
Participant Demographics
One 57-year-old female patient.
Digital Object Identifier (DOI)
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