N,N′-Bis(3β-acetoxy-5α-cholest-6-ylidene)hydrazine C58H96N2O4
2011
Study of a Cholesterol Derivative
publication
Evidence: moderate
Author Information
Author(s): Tabassum Zishan, Sulaiman Othman, Ibrahim M. N. Mohamad, Quah Ching Kheng, Fun Hoong-Kun
Primary Institution: Universiti Sains Malaysia
Hypothesis
The synthesis and crystal structure of a cholesterol derivative of hydrazine is investigated.
Conclusion
The study successfully synthesized and characterized the crystal structure of the compound N,N′-Bis(3β-acetoxy-5α-cholest-6-ylidene)hydrazine.
Supporting Evidence
- The compound was characterized using X-ray crystallography.
- Two independent molecules were found in the asymmetric unit.
- All cyclohexane rings in the compound are in chair conformations.
Takeaway
The researchers made a new compound related to cholesterol and looked at its structure using special techniques.
Methodology
The compound was synthesized through a reaction involving 3β-acetoxy-5α-cholestan-6-one and hydrazine hydrate, followed by crystallization.
Digital Object Identifier (DOI)
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