Inflammation Scores and Left Atrial Thrombosis in Stroke
Author Information
Author(s): Cicek Vedat, Kilic Sahhan, Dogan Selami, Erdem Almina, Babaoglu Mert, Yilmaz Irem, Karaismail Salih, Atmaca Murat Mert, Hayiroglu Mert Ilker, Cinar Tufan, Bagci Ulas, Lichtenauer Michael, Berezin Alexander E.
Primary Institution: Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University
Hypothesis
Can inflammation scores predict left atrial thrombosis in ischemic stroke patients without atrial fibrillation?
Conclusion
The C-reactive Protein–Albumin Ratio (CAR) is the best predictor of left atrial thrombosis in ischemic stroke patients without atrial fibrillation.
Supporting Evidence
- The CAR score was identified as the only independent predictor of left atrial thrombosis.
- Patients with left atrial thrombosis had significantly higher levels of inflammatory markers.
- Multivariate analysis showed that CAR, BNP, LAAP-D, and SPAP were significant predictors of left atrial thrombosis.
Takeaway
Doctors can use certain blood tests to help figure out if a patient with a stroke might have a blood clot in their heart.
Methodology
This was a single-center, retrospective study analyzing 303 patients with ischemic stroke who underwent transesophageal echocardiography.
Potential Biases
Potential biases due to the retrospective nature of the study and reliance on existing medical records.
Limitations
The study's retrospective design may introduce biases and confounding variables, and the sample size is relatively small.
Participant Demographics
Mean age was 68 years, with 58% male participants.
Statistical Information
P-Value
0.003
Confidence Interval
1.3874–5.2547
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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