Evaluation of LHP® (1% hydrogen peroxide) cream versus petrolatum and untreated controls in open wounds in healthy horses: a randomized, blinded control study
2011

Hydrogen Peroxide Cream for Wound Healing in Horses

Sample size: 10 publication 10 minutes Evidence: high

Author Information

Author(s): Tóth Tamás, Broström Hans, Båverud Viveca, Emanuelson Ulf, Bagge Elisabeth, Karlsson Tommy, Bergvall Kerstin

Primary Institution: Swedish University of Agricultural Sciences

Hypothesis

LHP® cream and white petrolatum could be beneficial for topical wound treatment and/or wound protection.

Conclusion

Treatment with LHP® reduced bacterial colonization and was associated with earlier complete wound healing.

Supporting Evidence

  • LHP® treated wounds healed significantly faster than petrolatum treated wounds.
  • Bacterial counts were significantly lower in LHP® treated wounds compared to untreated controls.
  • No adverse effects were reported for LHP® cream during the study.

Takeaway

Using a special cream with hydrogen peroxide helps horse wounds heal faster and stay cleaner than using regular petrolatum or no treatment at all.

Methodology

Standardized wounds were created in 10 Standardbred mares, treated with LHP® or petrolatum, and assessed daily until complete healing.

Potential Biases

Potential bias in treatment assignment and assessment due to the nature of the study design.

Limitations

The study was limited to healthy horses and may not apply to other conditions or species.

Participant Demographics

10 adult, healthy, non-pregnant Standardbred mares, mean age 14.8 years.

Statistical Information

P-Value

0.0004

Confidence Interval

95%CI = 26.9-37.7

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1751-0147-53-45

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