Case Report: Management of Polycaprolactone‐Based Dermal Filler–Induced Vascular Occlusion
2025

Management of Vascular Occlusion from Dermal Fillers

publication Evidence: low

Author Information

Author(s): Zaresharifi Shirin, Gheisari Mehdi, Mohammadzadeh Hamideh, Layegh Hojjat, Amani Maliheh

Primary Institution: Shahid Beheshti University of Medical Sciences

Hypothesis

Can early intervention effectively manage vascular occlusion caused by polycaprolactone-based dermal fillers?

Conclusion

Prompt treatment of vascular occlusion after PCL-based dermal filler injections can lead to successful resolution and prevent long-term damage.

Supporting Evidence

  • Vascular occlusion can occur due to direct injection into a vessel or external compression by the filler material.
  • Immediate treatment with hyaluronidase and corticosteroids is crucial for managing vascular occlusion.
  • Adjunctive treatments like PRP and laser therapy can enhance healing and minimize long-term cosmetic issues.

Takeaway

If someone gets a filler injection and their skin starts to change color or hurt, it's important to get help quickly to fix the problem and avoid lasting damage.

Methodology

The case involved a 42-year-old female treated for vascular occlusion with hyaluronidase, corticosteroids, anticoagulants, and laser therapy.

Limitations

The case report is based on a single patient, limiting generalizability.

Participant Demographics

One 42-year-old female patient.

Digital Object Identifier (DOI)

10.1111/jocd.16779

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