Effectiveness of T-PEMF with Antidepressants in Treatment-Resistant Patients
Author Information
Author(s): P. Bech, M. Gefke, M. Lunde, L. Lauritzen, K. Martiny
Primary Institution: Psychiatric Research Unit, Frederiksborg General Hospital, Denmark
Hypothesis
Does T-PEMF combined with antidepressants improve outcomes in treatment-resistant depression?
Conclusion
Active T-PEMF was found superior to sham T-PEMF with a clinically significant effect size.
Supporting Evidence
- 21 patients received active T-PEMF and 19 received sham T-PEMF.
- The effect size for active T-PEMF was 1.02 on HAM-D6.
- Active T-PEMF reduced concentration problems with an effect size of 0.44.
- Active T-PEMF had a clinically significant effect size level above 0.40.
Takeaway
This study shows that a special type of magnetic treatment can help people who don't get better with regular depression medicine.
Methodology
A double-blind, randomized, sham-controlled trial with 40 patients receiving either active or sham T-PEMF over five weeks.
Limitations
Five patients dropped out of the study, which may affect the results.
Participant Demographics
40 patients (12 males and 28 females) with treatment-resistant depression.
Statistical Information
P-Value
p ≤ 0.05
Statistical Significance
p ≤ 0.05
Digital Object Identifier (DOI)
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