Factors Associated with Nonadherence to HIV Therapy
Author Information
Author(s): Patrick S. Sullivan, Michael L. Campsmith, Glenn V. Nakamura, Elin B. Begley, Jeffrey Schulden, Allyn K. Nakashima
Primary Institution: Centers for Disease Control and Prevention
Hypothesis
What factors are associated with self-reported nonadherence to antiretroviral therapy among persons with HIV?
Conclusion
Self-reported nonadherence to antiretroviral therapy was high, indicating a need for increased emphasis on adherence in clinical settings.
Supporting Evidence
- 16% of respondents reported nonadherence to their HIV medication.
- Nonadherence was associated with factors like black race, Hispanic ethnicity, and living in a shelter.
- The median proportion of doses missed was 50%.
- Common reasons for missing doses included forgetting and side effects.
Takeaway
Many people with HIV forget to take their medicine or have side effects that make it hard to stick to their treatment plan.
Methodology
Data from a cross-sectional interview study of persons with HIV conducted in 18 U.S. states from 2000–2004 was analyzed using multivariate logistic regression.
Potential Biases
Recall bias and social desirability bias may lead to underreporting of nonadherence.
Limitations
The study is subject to recall and social desirability bias, and the sample may not be representative of all persons with HIV.
Participant Demographics
Participants included 72% male and 28% female, with a majority being black non-Hispanic (55%) and Hispanic (19%).
Statistical Information
Confidence Interval
95% CI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website