Impact of Type 2 Diabetes and Sleep Apnoea on Health Outcomes
Author Information
Author(s): David R. Riley, Alex Henney, Matthew Anson, Gema Hernandez, Sizheng S. Zhao, Uazman Alam, John P. H. Wilding, Sonya Craig, Daniel J. Cuthbertson
Primary Institution: University of Liverpool
Hypothesis
Does having both obstructive sleep apnoea (OSA) and type 2 diabetes (T2D) increase health risks compared to having either condition alone?
Conclusion
Having both T2D and OSA significantly increases the risk of cardiovascular disease, cancer, and liver-related outcomes compared to having either condition alone.
Supporting Evidence
- A codiagnosis of T2D/OSA significantly increased risk of all-cause mortality.
- Patients with both conditions had higher rates of dementia and various cancers.
- Microvascular complications were more prevalent in patients with both T2D and OSA.
Takeaway
If someone has both diabetes and sleep problems, they are more likely to get really sick compared to just having one of those problems.
Methodology
Two retrospective cohort studies using time-to-event analysis from a global health data network.
Potential Biases
Potential underreporting of conditions due to reliance on electronic medical records.
Limitations
The study relies on real-world data, which may include undiagnosed patients and variations in clinical practices.
Participant Demographics
Patients aged 18 and over from a global health data network, predominantly from the USA.
Statistical Information
Confidence Interval
1.48, 1.57
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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