Epidemiology and outcomes of community-onset methicillin-susceptible Staphylococcus aureus bacteraemia in a university hospital in Singapore
2008

Study of Staphylococcus aureus Infections in Singapore

Sample size: 100 publication Evidence: moderate

Author Information

Author(s): Chia Jonathan Wei-Zhong, Hsu Li-Yang, Chai Louis Yi-Ann, Tambyah Paul Ananth

Primary Institution: National University of Singapore

Hypothesis

What are the epidemiology and outcomes of community-onset methicillin-susceptible Staphylococcus aureus bacteraemia in Singapore?

Conclusion

MSSA bacteraemia is associated with a significant risk of serious complications in Singapore.

Supporting Evidence

  • 11% of patients died from the infection.
  • 46% of patients developed complicated bacteremia.
  • Age over 65 and chronic pulmonary disease were significant risk factors for mortality.

Takeaway

This study looked at a type of blood infection caused by a common germ and found that it can lead to serious health problems, especially for older people.

Methodology

A retrospective case series profiling all patients with community onset-MSSA bacteraemia presenting between March 2005 and February 2006.

Potential Biases

Potential bias due to retrospective design and reliance on medical records.

Limitations

The study is limited to a single center and may not be generalizable to other settings.

Participant Demographics

65% male, 69% below 65 years of age, with various co-morbidities including diabetes and intravenous drug abuse.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2334-8-14

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