The influence of age on the growth and spread of gastric carcinoma
1991

The Influence of Age on Gastric Carcinoma Growth

Sample size: 375 publication Evidence: moderate

Author Information

Author(s): C.W. Janssen Jr, R.T. Lie, H. Maartmann-Moe, R. Matre

Primary Institution: The Gade Institute, University of Bergen, Bergen, Norway

Hypothesis

Does the age of patients affect the growth and spread of gastric carcinoma?

Conclusion

Tumor spread in gastric carcinoma is age-dependent and varies between intestinal-type and diffuse tumors.

Supporting Evidence

  • Patients with diffuse tumors were generally younger than those with intestinal-type tumors.
  • Patients with intestinal-type tumors and metastases were younger than those without.
  • The age difference between the two tumor types was consistent across TNM classifications.

Takeaway

Older people with gastric cancer may have tumors that grow and spread differently than younger people, especially between two types of gastric cancer.

Methodology

A twelve-year study of 375 patients with gastric carcinoma, classified by TNM groups and tumor type.

Limitations

The study excluded patients with a history of other malignant diseases within the last 5 years.

Participant Demographics

62.4% of participants were men, with a mean age of 67.3 years.

Statistical Information

P-Value

0.0075

Statistical Significance

p=0.0075

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication