Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial
2024

Care Bundle for Intracerebral Hemorrhage: Evaluation Results

Sample size: 7036 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ouyang Menglu, Anjum Anila, Mc Cawley Francisca Gonzalez, Wasay Mohammad, Ma Lu, Hu Xin, Chen Xiaoying, Malavera Alejandra, Li Xi, Venturelli Paula Muñoz, de Silva H. Asita, Thang Nguyen Huy, Wahab Kolawole W., Pandian Jeyaraj D., Ponte-Neto Octavio M., Abanto Carlos, Cano-Nigenda Venessa, Arauz Antonio, You Chao, Jan Stephen, Song Lili, Anderson Craig S., Liu Hueiming

Primary Institution: The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, Australia

Hypothesis

Can a goal-directed multi-faceted Care Bundle improve functional recovery in patients with acute intracerebral hemorrhage?

Conclusion

The Care Bundle was generally delivered as planned and well accepted, but challenges in achieving physiological targets were noted.

Supporting Evidence

  • The Care Bundle included protocols for managing blood pressure, glucose, and body temperature.
  • Interviews and surveys indicated that the Care Bundle was well accepted by stakeholders.
  • Challenges included staff shortages and limited availability of medications.
  • Over 80% of patients reached the target for systolic blood pressure in most countries.

Takeaway

This study looked at how a special care plan helped patients with a type of stroke called intracerebral hemorrhage, showing it worked well but had some challenges.

Methodology

A mixed-methods approach including interviews, focus group discussions, and surveys was used to evaluate the implementation outcomes.

Potential Biases

Potential biases due to self-reported data and varying levels of healthcare infrastructure.

Limitations

Limited participant availability due to the COVID-19 pandemic and varying healthcare contexts across countries.

Participant Demographics

Participants included healthcare providers and patients from 8 low- and middle-income countries and 1 high-income country.

Statistical Information

P-Value

0.02

Confidence Interval

0.76 to 0.97

Statistical Significance

p=0.02

Digital Object Identifier (DOI)

10.1371/journal.pgph.0003711

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