Impact of Antibiotics on Rainbow Trout Gut Microbiome
Author Information
Author(s): Kim Min Kyo, Lee Yoonhang, Park Jiyeon, Lee Ju-Yeop, Kang Hyo-Young, Heo Young-Ung, Kim Do-Hyung
Primary Institution: Pukyong National University
Hypothesis
How does antibiotic treatment affect the fecal microbiome and antibiotic resistance in juvenile rainbow trout?
Conclusion
Antibiotic treatment alters the fecal microbiome and increases antibiotic resistance genes in rainbow trout, with changes persisting even after treatment cessation.
Supporting Evidence
- Antibiotic treatment disrupted the fecal microbial communities.
- OTC treatment increased the relative abundance of tet genes.
- Flavobacterium, Pseudomonas, and Streptococcus correlated with the abundance of ARGs.
- Microbial diversity did not stabilize even after a 25-day withdrawal period.
Takeaway
When rainbow trout take antibiotics, their poop changes a lot, and it stays different even after they stop taking the medicine.
Methodology
Fish were treated with antibiotics for 10 days, followed by a 25-day withdrawal period, with fecal samples collected at various time points for microbiome and ARG analysis.
Potential Biases
Potential bias in sampling methods and the specific antibiotics used.
Limitations
The study focused on short-term effects and may not capture long-term recovery dynamics.
Participant Demographics
Juvenile rainbow trout (Oncorhynchus mykiss) with an average weight of 20 ± 3.4 g.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website