Navigating new norms: Addiction specialists' perspectives on opioid use disorder treatments and policy challenges in the fentanyl era
2025

Addiction Specialists' Views on Opioid Use Disorder Treatments

Sample size: 91 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jeremy Weleff, Christian Nicholaus J., Wang James X., Singh Mohit, De Aquino Joao P., Saxon Andrew J., Vassallo Gabriela Garcia

Primary Institution: Yale University School of Medicine

Hypothesis

How have high-potency synthetic opioids influenced addiction specialists' clinical practices and their views on current regulations for opioid use disorder treatments?

Conclusion

Addiction specialists in the USA are open to integrating new treatment options for opioid use disorder, particularly slow-release oral morphine, to better address the challenges posed by fentanyl.

Supporting Evidence

  • 89% of respondents acknowledged that high-potency synthetic opioids have shifted addiction treatment.
  • 86% modified their prescribing practices due to the influence of fentanyl.
  • 80% expressed support for incorporating slow-release oral morphine as a treatment option.

Takeaway

Doctors who help people with addiction think new treatments for opioid problems are needed because of stronger drugs like fentanyl, and many are interested in using a different medicine called slow-release oral morphine.

Methodology

An anonymous online survey was conducted among addiction specialists attending a national conference.

Potential Biases

Responses may be biased due to the conference setting and the participants' specific interest in the topic.

Limitations

The sample may not represent all addiction specialists due to self-selection and the specific interest in slow-release oral morphine.

Participant Demographics

Most respondents were physicians (84%), predominantly White (70%), and nearly equal gender distribution (51% male, 46% female).

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1111/ajad.13653

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