The rate of TB-HIV co-infection depends on the prevalence of HIV infection in a community
2008

HIV Infection Rates in TB Patients and Pregnant Women in Southern Ethiopia

Sample size: 5507 publication Evidence: moderate

Author Information

Author(s): Datiko Daniel G, Yassin Mohammed A, Chekol Luelseged T, Kabeto Lopisso E, Lindtjørn Bernt

Primary Institution: Southern Nations, Nationalities and Peoples' Regional Health Bureau

Hypothesis

The study aims to determine the rate of HIV infection in TB patients and its correlation with the rate of HIV infection in pregnant women attending antenatal care in Southern Ethiopia.

Conclusion

The rate of HIV infection in TB patients and pregnant women was higher in study participants from urban areas.

Supporting Evidence

  • 18% of TB patients were HIV positive, with higher rates in urban areas.
  • 3.8% of pregnant women attending ANC were HIV positive, also higher in urban areas.
  • A strong correlation was found between HIV infection rates in TB patients and pregnant women in the same health institutions.

Takeaway

This study found that more people with tuberculosis (TB) in cities also had HIV, and the same was true for pregnant women visiting health clinics.

Methodology

A cross-sectional study was conducted with TB patients and pregnant women attending health institutions for diagnosis and treatment, with data collected through questionnaires and blood samples for HIV testing.

Potential Biases

Potential bias due to the exclusion of private clinics and low attendance at antenatal care.

Limitations

The study may not represent the entire population due to the exclusion of certain groups and reliance on health institution attendance.

Participant Demographics

Of the 1308 TB patients, 56% were men and 44% were women, with a mean age of 28.4 years; among 4199 pregnant women, 74% were from rural areas with a mean age of 25.7 years.

Statistical Information

P-Value

< 0.001

Confidence Interval

95%CI: 15.8 – 20.0 for TB patients; 95%CI: 3.2–4.4 for pregnant women

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2458-8-266

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