The ability of the prognostic nutritional index to predict short-term mortality in geriatric acute heart failure
2025

Predicting Short-Term Mortality in Elderly Heart Failure Patients

Sample size: 104 publication 10 minutes Evidence: moderate

Author Information

Author(s): Akça Hilal, Akça Hatice Şeyma, Özkan Abuzer, Özdemir Serdar

Primary Institution: Başakşehir Çam Ve Sakura City Hospital, İstanbul, Turkey

Hypothesis

Can the prognostic nutritional index (PNI) predict short-term mortality in geriatric patients with acute heart failure?

Conclusion

The low PNI group had a higher mortality rate, but PNI alone is not a strong prognostic marker.

Supporting Evidence

  • The study included 104 patients, with a 30-day mortality rate of 19.24%.
  • Patients with low PNI had a significantly higher mortality rate compared to those with high PNI.
  • Statistically significant differences were found in lymphocyte count, neutrophil-lymphocyte ratio, C-reactive protein, and albumin between high and low PNI groups.

Takeaway

This study looked at older patients with heart failure and found that those with lower nutritional scores were more likely to die soon, but the score alone isn't enough to predict outcomes.

Methodology

This was a single-center, retrospective study analyzing data from geriatric patients with acute heart failure treated in the emergency department.

Potential Biases

Potential biases due to the retrospective nature of the study and exclusion of patients with comorbidities.

Limitations

The retrospective design limits the ability to evaluate changes in PNI over time and generalize findings.

Participant Demographics

Patients aged 65 and older, with 57.7% females and 42.3% males.

Statistical Information

P-Value

0.032

Confidence Interval

95% CI: 0.30–0.83

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/s43044-024-00604-0

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication