Intrauterine Pressure Catheter in Labor: Associated Microbiology
1993

Bacterial Growth in Amniotic Fluid During Labor

Sample size: 20 publication Evidence: moderate

Author Information

Author(s): Phillip Pinell, Sebastian Faro, Scott Roberts, Sy Le, Maurizio Maccato, Hunter Hammill

Primary Institution: Baylor College of Medicine

Hypothesis

Does bacterial growth occur in the amniotic fluid of laboring women?

Conclusion

Bacterial species and colony counts increase significantly during labor, but this alone does not lead to chorioamnionitis in most patients.

Supporting Evidence

  • 80% of patients had a colony count greater than 102 cfu/cc.
  • Only 19% of patients with high bacterial counts developed chorioamnionitis.
  • The mean number of bacterial species increased from 0.9 to 1.8 during labor.

Takeaway

When women are in labor, bacteria can grow in the fluid around the baby, but just having more bacteria doesn't mean they will get sick.

Methodology

Amniotic fluid samples were taken from patients requiring an intrauterine pressure catheter during labor, with cultures analyzed for bacterial growth.

Limitations

The study did not explore the dynamic relationship between bacteria and amniotic fluid over time.

Participant Demographics

{"race":{"Black":3,"Hispanic":13,"White":3},"age":{"mean":26.5,"mode":24,"range":"14-40"},"gravidity":{"mean":3.2,"mode":2,"range":"1-9"},"parity":{"mean":1.2,"mode":0,"range":"0-6"}}

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

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