The Mating-Type Chromosome in the Filamentous Ascomycete Neurospora tetrasperma Represents a Model for Early Evolution of Sex Chromosomes
2008

Evolution of the Mating-Type Chromosome in Neurospora tetrasperma

Sample size: 152 publication Evidence: high

Author Information

Author(s): Menkis Audrius, Jacobson David J., Gustafsson Tim, Johannesson Hanna

Primary Institution: Swedish University of Agricultural Sciences

Hypothesis

The evolution of the mating-type chromosome in Neurospora tetrasperma involved two successive events of recombination suppression.

Conclusion

The study reveals that the mating-type chromosome in Neurospora tetrasperma has a large non-recombining region that evolved through two distinct evolutionary events.

Supporting Evidence

  • The non-recombining region covers almost 7 Mbp, over 75% of the chromosome.
  • The first event of recombination suppression was contemporaneous with the split of N. tetrasperma from N. crassa.
  • The study identified two evolutionary strata in the mating-type chromosome.

Takeaway

This study shows that the mating-type chromosome in a type of fungus has parts that don't mix genes like other chromosomes do, and this happened in two steps over time.

Methodology

The study combined gene divergence data, classical genetics, and phylogenetics to analyze the mating-type chromosome.

Statistical Information

P-Value

p<0.0015

Statistical Significance

p<0.0015

Digital Object Identifier (DOI)

10.1371/journal.pgen.1000030

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