Acute Kidney Injury in Older Patients After Heart Surgery
Author Information
Author(s): Michael Ried, Thomas Puehler, Assad Haneya, Christof Schmid, Claudius Diez
Primary Institution: University Medical Center Regensburg
Hypothesis
What is the incidence of acute kidney injury (AKI) and its impact on 30-day mortality in septuagenarians and octogenarians after cardiac surgery?
Conclusion
The RIFLE criteria can effectively identify patients at risk for acute kidney injury after cardiac surgery, and the incidence of AKI is high in both septuagenarians and octogenarians.
Supporting Evidence
- 21.7% of septuagenarians and 21.4% of octogenarians developed acute kidney injury.
- 30% of septuagenarians and 36.3% of octogenarians were at risk for AKI.
- Overall 30-day mortality was 6% in septuagenarians and 7.7% in octogenarians.
Takeaway
Older people often have kidney problems after heart surgery, and we can use a special scoring system to find out who is at risk.
Methodology
A retrospective study comparing 299 octogenarians and 299 septuagenarians who underwent cardiac surgery, assessing AKI incidence and 30-day mortality.
Potential Biases
Potential bias due to the retrospective design and exclusion of patients on preoperative renal replacement therapy.
Limitations
The study did not use urine output to classify renal function due to diuretic use, and the sample size was relatively small.
Participant Demographics
Patients aged 70 years and older, matched for gender and surgical procedure.
Statistical Information
P-Value
p < 0.001 for logistic EuroSCORE comparison
Confidence Interval
95% CI 0.35 to 3.08 for risk, 95% CI 1.1 to 8.2 for injury, 95% CI 4.5 to 39.9 for failure
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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