Bilirubin Levels and Kidney Function in Korean Adults
Author Information
Author(s): Shin Ho Sik, Jung Yeon Soon, Rim Hark
Primary Institution: Kosin University College of Medicine
Hypothesis
What is the relationship between serum bilirubin concentration, kidney function, and proteinuria in Korean adults?
Conclusion
Higher serum bilirubin concentration is associated with better kidney function and lower proteinuria in Korean adults.
Supporting Evidence
- Total serum bilirubin was positively associated with eGFR.
- Total serum bilirubin was negatively associated with proteinuria.
- 44.9% of subjects had fasting glucose levels ≥126 mg/dL.
- 26.1% of subjects had eGFR <60 mL/min/1.73 m2.
- 40.5% of subjects had 24-hour urine albumin ≥150 mg/day.
Takeaway
This study found that people with higher bilirubin levels tend to have healthier kidneys and less protein in their urine.
Methodology
The study reviewed medical records of Korean adults over five years, analyzing bilirubin levels, kidney function, and proteinuria.
Potential Biases
Potential biases include the retrospective nature of the study and lack of data on alcohol and smoking.
Limitations
The study's cross-sectional design limits causal conclusions and may not apply to the general population.
Participant Demographics
The sample included 1363 adults aged 18 years or older, with a mean age of 55.6 years, comprising 49.1% males and 50.9% females.
Statistical Information
P-Value
0.0001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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