3-(p-Tolyl)-4-{3-[(phenylamino)methyl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-yl}sydnone
2011
Study of a New Compound with Biological Potential
publication
Evidence: moderate
Author Information
Author(s): Fun Hoong-Kun, Quah Ching Kheng, Nithinchandra Kalluraya Balakrishna
Primary Institution: Universiti Sains Malaysia
Hypothesis
The introduction of a sydnone moiety into triazolothiadiazines will enhance their biological and pharmacological activities.
Conclusion
The synthesized compound exhibits a stable crystal structure with potential biological activity.
Supporting Evidence
- The compound's molecular structure is stabilized by an intramolecular hydrogen bond.
- The crystal structure shows dihedral angles indicating the orientation of rings in the compound.
- The study highlights the potential biological activities of sydnone derivatives.
Takeaway
Scientists made a new chemical compound that might help with medicine. They looked at how it is built and how it might work.
Methodology
The compound was synthesized through the condensation of specific chemical precursors and analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
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