Proteomic Analysis of the Fish Pathogen Vibrio ordalii Strain Vo-LM-18 and Its Outer Membrane Vesicles
2024
Proteomic Analysis of Vibrio ordalii and Its Outer Membrane Vesicles
Sample size: 3
publication
10 minutes
Evidence: high
Author Information
Author(s): Echeverría-Bugueño Macarena, Hernández Mauricio, Avendaño-Herrera Ruben
Primary Institution: Universidad Andrés Bello
Hypothesis
This study aimed to advance the proteomic knowledge of Chilean V. ordalii Vo-LM-18 and its outer membrane vesicles (OMVs).
Conclusion
The study reveals significant differences between the proteomes of V. ordalii strain Vo-LM-18 and its OMVs, highlighting a higher abundance of virulence and transport proteins in OMVs.
Supporting Evidence
- 2242 proteins were identified in V. ordalii Vo-LM-18 and 1755 proteins in its OMVs.
- OMVs expressed a higher number of virulence-associated proteins.
- This is the first detection of the RTX toxin in a V. ordalii strain.
Takeaway
Scientists studied a fish germ that makes fish sick and found that tiny bubbles it releases have special proteins that help it infect fish better.
Methodology
The study used Nano-UHPLC-LC-MS/MS to identify proteins in V. ordalii and its OMVs.
Statistical Information
P-Value
0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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