Increased Risk for Entamoeba histolytica Infection in HIV-Positive Men Who Have Sex with Men in Taiwan
Author Information
Author(s): Hung Chien-Ching, Ji Dar-Der, Sun Hsin-Yun, Lee Ya-Tien, Hsu Shui-Yuan, Chang Sui-Yuan, Wu Cheng-Hsin, Chan Yun-Hsien, Hsiao Chin-Fu, Liu Wen-Chun, Colebunders Robert
Primary Institution: National Taiwan University Hospital
Hypothesis
HIV-infected men who have sex with men (MSM) are at a higher risk of acquiring Entamoeba histolytica infection compared to other risk groups.
Conclusion
HIV-infected MSM are at significantly higher risk of amebiasis than patients from other risk groups, and treatment with metronidazole is effective.
Supporting Evidence
- 64 out of 1109 HIV-infected patients were diagnosed with invasive amebiasis.
- 89.1% of the patients with invasive amebiasis were men who have sex with men.
- The incidence of E. histolytica infection in MSM was significantly higher than in other risk groups.
Takeaway
This study found that gay men with HIV are more likely to get a certain infection called amebiasis, but they can get better with medicine.
Methodology
The study reviewed medical records of HIV-infected patients diagnosed with invasive amebiasis and analyzed blood and stool samples for E. histolytica infection.
Potential Biases
The study may be biased due to the retrospective design and the referral nature of the hospital.
Limitations
The study's findings may not be generalizable to areas with higher endemicity of E. histolytica and the sample size for some analyses was small.
Participant Demographics
The study included 1109 HIV-infected patients, with 70.4% being men who have sex with men.
Statistical Information
P-Value
p<0.0001
Confidence Interval
95% CI, 1.5777, 7.417
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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