GLYNAC SUPPLEMENTATION IN OLDER ADULTS IMPROVES GLUTATHIONE, MITOCHONDRIA, AGING HALLMARKS, AND FUNCTION
2024
GlyNAC Supplementation Improves Aging in Older Adults
Sample size: 36
publication
Evidence: high
Author Information
Author(s): Sekhar Rajagopal, Kumar Premranjan, Taffet George, Minard Charles, Suliburk James, Jahoor Farook, Liu Chun, Muthupillai Raja
Primary Institution: Baylor College of Medicine
Hypothesis
Can GlyNAC supplementation improve oxidative stress, mitochondrial dysfunction, and physical function in older adults?
Conclusion
GlyNAC supplementation in older adults for 16 weeks was safe and effective in reversing multiple age-related declines.
Supporting Evidence
- GlyNAC supplementation improved GSH deficiency in older adults.
- Participants showed reduced oxidative stress and improved mitochondrial function.
- The study included both older and young adults to compare effects.
Takeaway
Giving older people a supplement called GlyNAC can help them feel better and healthier as they age.
Methodology
A placebo-controlled randomized clinical trial with 24 older adults and 12 young adults over 16 weeks.
Participant Demographics
24 older adults and 12 young adults participated in the study.
Digital Object Identifier (DOI)
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