Survival Analysis of Long-Term Exposure to Different Sizes of Airborne Particulate Matter and Risk of Infant Mortality Using a Birth Cohort in Seoul, Korea
2011

Air Pollution and Infant Mortality in Seoul, Korea

Sample size: 359459 publication 10 minutes Evidence: moderate

Author Information

Author(s): Son Ji-Young, Bell Michelle L., Lee Jong-Tae

Primary Institution: Yale University

Hypothesis

Is long-term exposure to different sizes of airborne particulate matter associated with infant mortality?

Conclusion

Long-term exposure to particulate matter air pollution is associated with increased risk of infant mortality.

Supporting Evidence

  • Gestational exposure to PM was linked to increased infant mortality from all causes.
  • Risks for respiratory mortality were significantly higher for normal-birth-weight infants.
  • Statistically significant associations were found for TSP, PM10, and PM2.5.

Takeaway

Breathing dirty air for a long time can make babies more likely to die, especially if they are born with a normal weight.

Methodology

The study used extended Cox proportional hazards modeling to analyze mortality data from a birth cohort.

Potential Biases

Potential biases may arise from unmeasured confounding factors related to socioeconomic status.

Limitations

The study may not fully account for all potential confounders, such as maternal smoking, and the small number of deaths limited the analysis.

Participant Demographics

The cohort included 359,459 births, with 2.0% low birth weight infants.

Statistical Information

P-Value

p<0.05

Confidence Interval

1.06–1.97 for all causes, 1.18–12.13 for respiratory causes

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.1002364

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