A protocol for enumeration of aquatic viruses by epifluorescence microscopy using Anodiscâ„¢ 13 membranes
2011

Counting Aquatic Viruses with New Membranes

publication Evidence: moderate

Author Information

Author(s): Budinoff Charles R, Loar Star N, LeCleir Gary R, Wilhelm Steven W, Buchan Alison

Primary Institution: Department of Microbiology, University of Tennessee, Knoxville, Tennessee, USA

Hypothesis

Can 13 mm Anodisc membranes be effectively used for enumerating virus-like particles in aquatic samples?

Conclusion

The 13 mm Anodisc membranes are cost-effective and suitable for large-scale studies of virus-like particles in environmental samples.

Supporting Evidence

  • The 13 mm Anodisc membranes provided comparable estimates of virus-like particle abundance to the 25 mm membranes.
  • Using Nuclepore membranes typically resulted in lower virus-like particle counts.
  • The modified protocol allows for high throughput filtration and is cost-effective.

Takeaway

This study shows that smaller filters can be used to count viruses in water, which saves money and uses less water.

Methodology

The study developed a protocol using 13 mm Anodisc membranes for counting virus-like particles, comparing results with 25 mm Anodisc and Nuclepore membranes.

Limitations

The lack of a support ring on the 13 mm membranes can complicate handling.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2180-11-168

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