Fermented Fish Collagen Reduces Skin Aging Effects
Author Information
Author(s): Oh Seyeon, Lee So Young, Jang Jong-Won, Son Kuk Hui, Byun Kyunghee, Popławski Tomasz
Primary Institution: Gachon University
Hypothesis
Fermented fish collagen decreases photoaging by reducing RAGE activity.
Conclusion
Fermented fish collagen can mitigate skin photoaging by decreasing AGE–RAGE binding activity and its associated inflammatory signals.
Supporting Evidence
- UV irradiation increases skin aging by promoting oxidative stress.
- Fermented fish collagen decreased TNF-α levels in UV-irradiated skin.
- Collagen accumulation in the skin was enhanced by fermented fish collagen treatment.
- Fermented fish collagen reduced the expression of matrix metalloproteinases associated with collagen degradation.
Takeaway
Eating fermented fish collagen can help keep your skin looking young by stopping damage from sunlight.
Methodology
The study involved in vitro tests on human keratinocytes and in vivo tests on UV-irradiated mice to assess the effects of fermented fish collagen on skin aging.
Limitations
The long-term safety of fermented fish collagen was not evaluated in this study.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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