Diabetes Mellitus: A Risk Factor in Schlemm’s Canal-Based Minimally Invasive Glaucoma Surgery
2024

Diabetes and Glaucoma Surgery Outcomes

Sample size: 109 publication Evidence: moderate

Author Information

Author(s): Chihara Etsuo, Nakano Eri, Chihara Tomoyuki

Primary Institution: Sensho-kai Eye Institute

Hypothesis

Does diabetes mellitus affect the outcomes of Schlemm’s canal-based minimally invasive glaucoma surgery?

Conclusion

Diabetes mellitus is a significant risk factor for poor outcomes following Schlemm’s canal-based MIGS, particularly in achieving lower postoperative intraocular pressure.

Supporting Evidence

  • The post-surgical intraocular pressure was significantly higher in the cohort with diabetes.
  • The 3-year survival probability of achieving an IOP ≤ 15 mmHg was significantly lower in patients with diabetes.
  • Diabetes emerged as a significant risk factor for higher postoperative IOP at both 6 and 12 months.

Takeaway

If you have diabetes and need eye surgery for glaucoma, it might not work as well for you as it does for people without diabetes.

Methodology

A retrospective interventional cohort study analyzing postoperative intraocular pressure and intracameral bleeding in diabetic and non-diabetic patients.

Potential Biases

The retrospective design may introduce biases that could affect the results.

Limitations

The sample size of subjects with diabetes is relatively small, and the retrospective design may introduce unforeseen biases.

Participant Demographics

25 diabetic patients and 84 non-diabetic patients with primary open-angle glaucoma or ocular hypertension.

Statistical Information

P-Value

p = 0.001 to 0.042

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/jcm13247660

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