CARDIOMETABOLIC DISEASE RISK PARTIALLY MEDIATES RELATIONSHIP BETWEEN FINE PARTICULATE MATTER AND COGNITION
2024

Impact of Air Pollution on Aging and Cognition

Sample size: 4272 publication Evidence: moderate

Author Information

Author(s): Cheung Ethan Siu Leung, Grineski Sara, Curtis David

Primary Institution: University of Utah

Hypothesis

How does cardiometabolic disease risk mediate the relationship between fine particulate matter exposure and cognitive decline in older adults?

Conclusion

Higher exposure to PM2.5 is linked to lower executive functioning in older adults, with cardiometabolic disease risk partially mediating this relationship.

Supporting Evidence

  • PM2.5 exposure is associated with many adverse health effects.
  • Higher PM2.5 exposure was linked to lower executive functioning.
  • Cardiometabolic disease risk accounted for 14% of the association between PM2.5 and executive functioning.

Takeaway

Breathing in dirty air can make it harder for older people to think clearly, and health issues like heart disease can make this worse.

Methodology

Longitudinal data from the MIDUS study were used to analyze the effects of PM2.5 exposure on cognitive functioning and daily living activities.

Limitations

The study did not find significant associations between PM2.5 and IADL limitations.

Participant Demographics

Individuals aged 32 to 84 from the United States.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.3038

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