Low prevalence of Epstein–Barr virus in incident gastric adenocarcinomas from the United Kingdom
2002

Low prevalence of Epstein–Barr virus in gastric adenocarcinomas in the UK

Sample size: 534 publication Evidence: moderate

Author Information

Author(s): D E Burgess, C B Woodman, K J Flavell, D C Rowlands, J Crocker, K Scott, J P Biddulph, L S Young, P G Murray

Primary Institution: University of Birmingham

Hypothesis

The prevalence of Epstein–Barr virus in gastric adenocarcinomas from the United Kingdom is one of the lowest in the world.

Conclusion

The study found that only 1.7% of gastric adenocarcinomas in the UK were positive for Epstein–Barr virus.

Supporting Evidence

  • Only 1.7% of the gastric adenocarcinomas tested positive for Epstein–Barr virus.
  • The study included 534 patients diagnosed with gastric adenocarcinoma.
  • The mean age of patients was 65.4 years.
  • The male to female ratio among participants was 2.2:1.

Takeaway

This study looked at stomach cancer cases in the UK and found that very few had a virus called Epstein–Barr, which is linked to some stomach cancers.

Methodology

The study involved a survey of 534 patients diagnosed with gastric adenocarcinoma, determining EBV status through tissue samples.

Limitations

The study may not represent all gastric adenocarcinomas as it was conducted in a specific region and time frame.

Participant Demographics

The mean age of patients was 65.4 years, with a male to female ratio of 2.2:1.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600107

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