Anticancer Effects of Adiantum venustum
Author Information
Author(s): D. Viral, P. Jivani
Primary Institution: Smt. R. B. P. Mahila Pharmacy College
Hypothesis
The study aims to evaluate the anticancer activity of Adiantum venustum against Ehrlich Ascites Carcinoma in an animal model.
Conclusion
The ethanolic extract of Adiantum venustum shows significant anticancer activity and reduces lipid peroxidation levels.
Supporting Evidence
- Ethanolic extract of A. venustum significantly increased the mean survival time of treated mice.
- The extract reduced tumor volume and viable tumor cell count in a dose-dependent manner.
- Hematological parameters improved in extract-treated mice compared to control.
- The extract significantly decreased lipid peroxidation levels in EAC-bearing mice.
Takeaway
This study found that a plant called Adiantum venustum can help fight cancer in mice by making them healthier and reducing tumor size.
Methodology
The study involved administering different doses of ethanolic extract to mice and observing their effects on tumor growth and survival.
Limitations
The study was conducted on mice, and results may not directly translate to humans.
Participant Demographics
Male Swiss albino mice weighing 20–25 g.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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