A review of the off-label use of selamectin (Stronghold®/Revolution®) in dogs and cats
2008

Review of Selamectin Use in Dogs and Cats

publication Evidence: moderate

Author Information

Author(s): Maggie A Fisher, David J Shanks

Hypothesis

Selamectin can be effectively used off-label to treat various ecto- and endoparasite conditions in dogs and cats.

Conclusion

Selamectin has been shown to be effective and well-tolerated for treating a range of parasitic infections in dogs and cats.

Supporting Evidence

  • Selamectin has been used successfully to treat various ectoparasites like fleas and mites in dogs and cats.
  • It has shown efficacy against endoparasites such as Dirofilaria repens and Aelurostrongylus abstrusus.
  • Selamectin is well-tolerated even in sensitive breeds like ivermectin-sensitive collies.

Takeaway

Selamectin is a medicine that helps pets get rid of bugs that make them sick, and it works well for many types of infections.

Methodology

The review summarizes various reports on the off-label use of selamectin in treating different parasites in dogs and cats.

Potential Biases

Potential bias due to financial support from Pfizer Animal Health.

Limitations

The review does not provide specific data on the effectiveness of selamectin for all conditions, particularly for generalized demodicosis.

Digital Object Identifier (DOI)

10.1186/1751-0147-50-46

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