Primary Effusion Lymphoma in an HIV-Infected Woman from Uganda
Author Information
Author(s): Tumwine Lynnette K, Lalitha Rejani, Agostinelli Claudio, Luzige Simon, Orem Jackson, Piccaluga Pier Paolo, Osuwat Lawrence O, Pileri Stefano A
Primary Institution: Makerere University College of Health Sciences, Uganda
Hypothesis
This case report aims to document the occurrence of primary effusion lymphoma in sub-Saharan Africa, particularly in an HIV-positive patient.
Conclusion
This case highlights the need for increased awareness and diagnostic capabilities for primary effusion lymphoma in HIV-positive patients in sub-Saharan Africa.
Supporting Evidence
- Primary effusion lymphoma is a rare type of cancer associated with HIV.
- This case is the first report of primary effusion lymphoma in sub-Saharan Africa.
- The patient had a low CD4 count of 127/μL, indicating advanced HIV disease.
- Immunohistochemistry confirmed the presence of HHV-8 in the tumor cells.
Takeaway
A 70-year-old woman with HIV in Uganda was found to have a rare type of cancer called primary effusion lymphoma, which is often missed in patients without visible tumors.
Methodology
The diagnosis was made through clinical examination, cytomorphologic analysis, and immunohistochemistry.
Limitations
Immunohistochemistry is not routinely available in Uganda, which may hinder diagnosis.
Participant Demographics
The participant was a 70-year-old HIV-positive Ugandan woman.
Digital Object Identifier (DOI)
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