Vaccination coverage and timeliness in three South African areas: a prospective study
2011

Vaccination Coverage and Timeliness in South Africa

Sample size: 1137 publication Evidence: moderate

Author Information

Author(s): Fadnes Lars T, Jackson Debra, Engebretsen Ingunn MS, Zembe Wanga, Sanders David, Sommerfelt Halvor, Tylleskär Thorkild

Primary Institution: Centre for International Health, University of Bergen, Norway

Hypothesis

How does vaccination coverage and timeliness vary across different geographical areas in South Africa?

Conclusion

Vaccination coverage and timeliness vary significantly across different areas in South Africa, with poorer regions showing lower rates.

Supporting Evidence

  • Vaccination coverage was 94% in Paarl, 88% in Umlazi, and 62% in Rietvlei.
  • Timeliness of vaccination was lower for vaccines given at older ages.
  • The hazard ratio for incomplete vaccination was 7.2 for Rietvlei compared to Paarl.
  • Most vaccinations were collected from health cards, with 98% of children having their cards checked.

Takeaway

This study looked at how many kids got their vaccines on time in different parts of South Africa, finding that kids in poorer areas got fewer vaccines.

Methodology

The study used vaccination data from a community-based cluster-randomized trial and followed 1137 children over 18 months.

Potential Biases

Some children who died during follow-up may have had different vaccination statuses compared to those who survived.

Limitations

The timing of measles vaccination data may be biased due to a missed question in the survey.

Participant Demographics

Participants included mother-infant pairs from three areas: Paarl, Umlazi, and Rietvlei, with varying socioeconomic conditions.

Statistical Information

Confidence Interval

95% CI for coverage rates varied by site.

Digital Object Identifier (DOI)

10.1186/1471-2458-11-404

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