Hypertension in the Elderly
2012

Hypertension in the Elderly

Sample size: 4227 publication Evidence: high

Author Information

Author(s): Blas Gil-Extremera, Pedro Cía-Gómez

Primary Institution: San Cecilio University Hospital, Granada, Spain

Hypothesis

Should aged people receive pharmacological treatment for hypertension similarly to younger patients?

Conclusion

Hypertension is the most prevalent cardiovascular disorder in the Western countries, and pharmacological treatment is crucial for aged patients, with combination therapy showing more benefits than monotherapy.

Supporting Evidence

  • The Syst-Eur trial showed a 50% reduction in dementia incidence with antihypertensive treatment.
  • Combination therapy of nitrendipine plus enalapril may provide better outcomes than nitrendipine alone.
  • HYVET trial demonstrated the benefits of treating hypertension in patients aged 80 or older.

Takeaway

High blood pressure is a big problem for older people, and treating it can help them live longer and healthier lives.

Methodology

Analysis of significant clinical trials related to hypertensive populations.

Limitations

Few studies have included treatment of hypertension in patients aged 80 or older.

Participant Demographics

Patients aged 60 or older, with a focus on those aged 80 or older.

Statistical Information

P-Value

0.05

Statistical Significance

p=0.05

Digital Object Identifier (DOI)

10.1155/2012/859176

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